Orange are unable to keep up with the Wildcats, considered one of the nation’s best offenses.
After taking care of Georgetown 14-8, SU will face 4th-seeded Northwestern on Saturday.
The women’s team earned a 5-seed in the tournament.
The Orange fell in the final seconds to undefeated Boston College.
This loss comes a week and a half after the Orange defeated UNC during a regular season matchup.
The two teams were tied 6-6 at halftime.
The Orange will finish its ACC schedule with a trip to North Carolina to take on the Tar Heels this weekend.
Virginia Tech scored four straight goals in the last seven and a half minutes of the game to bring the Orange within one.
Syracuse dominated draw controls, winning 20-7.