The Orange outscored Clemson 30-22 in the first half to give Syracuse a stable lead for the rest of the game.
Tiana Mangakahia scored a season-high 27 points.
Bourama Sidibe made big plays after Syracuse big men Marek Dolezaj and Paschal Chukwu fouled out.
Buddy Boeheim scored a career-high 12 points.
This is the Orange’s first win since the Dec. 8 contest against Georgetown.
The Bulls went on a 16-6 run in the last seven minutes of the game.
Miranda Drummond ended with a game-high 19 points.
The Orange missed 12 free throws and went 16-48 in field goals.
The Orange came back after a sloppy first half to score 50 points against the Hoyas.